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DNA ligase IV: homologous recombination mend and essential in immune mobile growth and also other functions critical to a standard cell.
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DNA ligases have become indispensable resources in contemporary molecular biology study for generating recombinant DNA sequences. One example is, DNA ligases are utilized with restriction enzymes to insert DNA fragments, typically genes, into plasmids.
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DNA ligase three: complexes with DNA maintenance protein XRCC1 to help in sealing DNA all through the whole process of nucleotide excision repair and recombinant fragments. From the all identified mammalian DNA ligases, only ligase three is discovered to be current in mitochondria.
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